| Round | Pick | Name | Starts | Points | PPG |
|---|---|---|---|---|---|
| 1 | 1 | Justin Jefferson | 17 | 165.20 | 9.72 |
| 2 | 20 | Joe Mixon | 16 | 242.30 | 14.25 |
| 3 | 21 | Patrick Mahomes | 16 | 326.22 | 19.19 |
| 4 | 40 | Miles Sanders | 5 | 83.80 | 4.93 |
| 5 | 41 | T.J. Hockenson | 16 | 218.00 | 12.82 |
| 6 | 60 | James Cook | 15 | 228.50 | 13.44 |
| 7 | 61 | Marquise Brown | 3 | 134.70 | 7.92 |
| 8 | 80 | Garrett Wilson | 13 | 205.80 | 12.11 |
| 9 | 81 | Jakobi Meyers | 7 | 198.98 | 11.70 |
| 10 | 100 | Zay Flowers | 10 | 206.40 | 12.14 |
| 11 | 101 | Treylon Burks | 2 | 16.80 | 2.80 |
| 12 | 120 | Jerick McKinnon | 1 | 66.06 | 8.26 |
| 13 | 121 | Cowboys D/ST | 10 | 173.00 | 10.18 |
| 14 | 140 | Ezekiel Elliott | 1 | 90.60 | 11.33 |
| 15 | 141 | Tyler Bass | 12 | 83.00 | 6.92 |
| 16 | 160 | Anthony Richardson | 0 | 76.68 | 12.78 |